ITGA5 抗体 (Cleaved-Arg894, Heavy Chain)
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北京 101111
Quick Overview for ITGA5 抗体 (Cleaved-Arg894, Heavy Chain) (ABIN8122270)
抗原
See all ITGA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cleaved-Arg894, Heavy Chain
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原理
- ITGA5 (heavy chain, Cleaved-Arg894) Antibody
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特异性
- This antibody detects endogenous levels of Human,Mouse ITGA5 (heavy chain, Cleaved-Arg894, protein was cleaved amino acid sequence between 894-895 )
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human ITGA5 (heavy chain, Cleaved-Arg894)
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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别名
- ITGA5
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背景
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Synonyms: Integrin alpha-5 (CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain, Integrin alpha-5 light chain]
Background: function:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat. Interacts with RAB21.,
Gene Name: ITGA5 FNRA
Protein Name: ITGA5 (heavy chain, Cleaved-Arg894)
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基因ID
- 3678
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UniProt
- P08648
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途径
- Integrin Complex
抗原
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