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HBEGF 抗体 (AA 130-210)

This 兔 多克隆 antibody specifically detects HBEGF in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8121929
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HBEGF 抗体 (AA 130-210) (ABIN8121929)

抗原

See all HBEGF 抗体
HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

适用

  • 104
  • 35
  • 35
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 98
  • 19
  • 5
  • 1
兔

克隆类型

  • 91
  • 27
  • 3
多克隆

标记

  • 49
  • 11
  • 9
  • 6
  • 6
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This HBEGF antibody is un-conjugated

应用范围

  • 48
  • 28
  • 28
  • 26
  • 22
  • 13
  • 10
  • 10
  • 7
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 27
    • 15
    • 15
    • 12
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 130-210

    原理

    HBEGF Antibody

    特异性

    HBEGF Polyclonal Antibody detects endogenous levels of protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human protein . at AA range: 130-210

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

    别名

    HBEGF

    背景

    Background: function:May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.,PTM:O-linked glycan attachment sites were determined by Edman degradation, O-glycanase digest suggests mucin-type glycosylation (done in HB-EGF purified from histiocytic lymphoma cell line U-937).,PTM:Several N-termini have been identified by direct sequencing. The forms with N-termini 63, 73 and 74 have been tested and found to be biologically active.,similarity:Contains 1 EGF-like domain.,subcellular location:Mature HB-EGF is released into the extracellular space and probably binds to a receptor.,

    Gene Name: HBEGF DTR DTS HEGFL

    Protein Name: Proheparin-binding EGF-like growth factor [Cleaved into: Heparin-binding EGF-like growth factor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R)]

    基因ID

    1839

    UniProt

    Q99075

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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