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PSMA 抗体 (AA 100-200)

This 小鼠 单克隆 antibody specifically detects PSMA in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8121485
发货至: 中国
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Quick Overview for PSMA 抗体 (AA 100-200) (ABIN8121485)

抗原

See all PSMA (FOLH1) 抗体
PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

适用

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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 68
  • 67
  • 12
  • 1
  • 1
小鼠

克隆类型

  • 113
  • 33
  • 3
单克隆

标记

  • 102
  • 5
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  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
This PSMA antibody is un-conjugated

应用范围

  • 81
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  • 36
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  • 10
  • 4
  • 2
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

克隆位点

AB1585
  • 抗原表位

    • 36
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-200

    原理

    Prostate Specific Membrane Antigen (PSMA) mouse mAb

    特异性

    The antibody can specifically recognize human PSMA protein. In western blotting of LnCap, Hela and MCF7 cell lysates, the antibody can label a specific band corresponding to PSMA only in LnCap cell lysates.

    纯化方法

    The antibody was purified by protein G affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 100 - 200 of the human Prostate Specific Membrane Antigen protein.

    亚型

    IgG
  • 应用备注

    IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

    别名

    Prostate Specific Membrane Antigen

    背景

    Synonyms: Cell growth inhibiting protein 27, Cell growth-inhibiting gene 27 protein, FGCP, Folate hydrolase (prostate-specific membrane antigen) 1, Folate hydrolase 1, Folate hydrolase, Folate hydrolase prostate specific membrane antigen 1, FOLH 1, FOLH, Folh1, FOLH1_HUMAN, Folylpoly gamma glutamate carboxypeptidase, Folylpoly-gamma-glutamate carboxypeptidase, GCP 2, GCP II, GCP2, GCPII, GIG27, Glutamate carboxylase II, Glutamate carboxypeptidase 2, Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, mGCP, N acetylated alpha linked acidic dipeptidase 1, N-acetylated-alpha-linked acidic dipeptidase I, NAALAD 1, NAALAD1, NAALAdase, NAALADase I, Prostate specific membrane antigen, Prostate specific membrane antigen variant F, Prostate-specific membrane antigen, PSM, PSMA, Pteroylpoly gamma glutamate carboxypeptidase, Pteroylpoly-gamma-glutamate carboxypeptidase

    Background: This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]

    Gene Name: FOLH1

    Protein Name: Prostate Specific Membrane Antigen

    基因ID

    2346

    UniProt

    Q04609
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