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PSMA 抗体 (AA 232-433)

The 小鼠 单克隆 anti-PSMA antibody is suitable to detect PSMA in samples from 人, 犬, 马 和 Cat. It has been validated for WB 和 IHC.
产品编号 ABIN6939424
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for PSMA 抗体 (AA 232-433) (ABIN6939424)

抗原

See all PSMA (FOLH1) 抗体
PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

适用

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人, 犬, 马, Cat

宿主

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小鼠

克隆类型

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单克隆

标记

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This PSMA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

FOLH1-2354
  • 抗原表位

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    AA 232-433

    原理

    FOLH1 / PSMA (Prostate Epithelial Marker) Antibody

    特异性

    Folate hydrolase 1 (FOLH1), also known as Prostate-specific membrane antigen (PSMA), is a type II transmembrane glycoprotein belonging to the M28 peptidase family. FOLH1 has two enzymatic activities, one as a prostate-specific integral membrane folate hydrolase and the other as a carboxypeptidase In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant human FOLH1 protein fragment (around aa 232-433) (exact sequence is proprietary)

    亚型

    IgG2b, kappa
  • 应用备注

    Positive Control: LNCap or HepG2 cells. Prostate Carcinoma.

    Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

    别名

    FOLH1

    背景

    Cell growth-inhibiting gene 27 protein (GIG27), Folate hydrolase 1 (FOLH1), Folylpoly-gamma-glutamate carboxypeptidase (FGCP), Glutamate carboxylase II (GCPII), Glutamate carboxypeptidase 2 (GCP2), Glutamate carboxypeptidase II Membrane glutamate carboxypeptidase N-acetylated-alpha-linked acidic dipeptidase I (NAALAD1 or NAALADase), Prostate-specific membrane antigen (PSM or PSMA), Pteroylpoly-gamma-glutamate carboxypeptidase

    LNCap or HepG2 cells. Prostate Carcinoma.

    分子量

    100kDa

    基因ID

    2346, 654487

    UniProt

    Q04609
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