PSMA 抗体 (AA 232-433)
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北京 101111
Quick Overview for PSMA 抗体 (AA 232-433) (ABIN6939424)
抗原
See all PSMA (FOLH1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 232-433
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原理
- FOLH1 / PSMA (Prostate Epithelial Marker) Antibody
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特异性
- Folate hydrolase 1 (FOLH1), also known as Prostate-specific membrane antigen (PSMA), is a type II transmembrane glycoprotein belonging to the M28 peptidase family. FOLH1 has two enzymatic activities, one as a prostate-specific integral membrane folate hydrolase and the other as a carboxypeptidase In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human FOLH1 protein fragment (around aa 232-433) (exact sequence is proprietary)
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亚型
- IgG2b, kappa
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应用备注
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Positive Control: LNCap or HepG2 cells. Prostate Carcinoma.
Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))
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别名
- FOLH1
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背景
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Cell growth-inhibiting gene 27 protein (GIG27), Folate hydrolase 1 (FOLH1), Folylpoly-gamma-glutamate carboxypeptidase (FGCP), Glutamate carboxylase II (GCPII), Glutamate carboxypeptidase 2 (GCP2), Glutamate carboxypeptidase II Membrane glutamate carboxypeptidase N-acetylated-alpha-linked acidic dipeptidase I (NAALAD1 or NAALADase), Prostate-specific membrane antigen (PSM or PSMA), Pteroylpoly-gamma-glutamate carboxypeptidase
LNCap or HepG2 cells. Prostate Carcinoma.
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分子量
- 100kDa
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基因ID
- 2346, 654487
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UniProt
- Q04609
抗原
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