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EPAS1 抗体 (Lys385)

The 兔 多克隆 anti-EPAS1 antibody is suitable to detect EPAS1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN8121183
发货至: 中国
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北京 101111
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for EPAS1 抗体 (Lys385) (ABIN8121183)

抗原

See all EPAS1 抗体
EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This EPAS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    Lys385

    原理

    EPAS-1 Antibody

    特异性

    EPAS-1 Polyclonal Antibody detects endogenous levels of EPAS-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human EPAS-1 around the non-acetylation site of K385.

    亚型

    IgG
  • 应用备注

    IF 1:50-200 WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

    别名

    EPAS-1

    背景

    Synonyms: EPAS1, BHLHE73, HIF2A, MOP2, PASD2, Endothelial PAS domain-containing protein 1, EPAS-1, Basic-helix-loop-helix-PAS protein MOP2, Class E basic helix-loop-helix protein 73, bHLHe73, HIF-1-alpha-like factor, HLF, Hypoxia-inducible factor 2-alpha, HIF-2-alpha, HIF2-alpha, Member of PAS protein 2, PAS domain-containing protein 2

    Background: endothelial PAS domain protein 1(EPAS1) Homo sapiens This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009],

    Gene Name: EPAS1 BHLHE73 HIF2A MOP2 PASD2

    Protein Name: Endothelial PAS domain-containing protein 1

    基因ID

    2034

    UniProt

    Q99814

    途径

    Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
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