p300 抗体 (AA 1-100)
Our Local Distributor
北京 101111
Quick Overview for p300 抗体 (AA 1-100) (ABIN8121098)
抗原
See all p300 (EP300) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-100
-
原理
- p300 mouse mAb
-
特异性
- This antibody detects endogenous levels of p300 protein.
-
纯化方法
- The antibody was purified by protein G affinity chromatography.
-
免疫原
- A synthetic peptide corresponding to the amino acid region 1 - 100 of the human p300 protein.
-
亚型
- IgG
-
-
-
-
应用备注
- WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid freeze / thaw cycles
-
储存条件
- -20 °C
-
储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
-
-
- p300 (EP300) (E1A Binding Protein P300 (EP300))
-
别名
- p300
-
背景
-
Synonyms: EP300, P300, Histone acetyltransferase p300, p300 HAT, E1A-associated protein p300
Background: E1A binding protein p300 (EP300) Homo sapiens This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha) , and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008],
Gene Name: EP300
Protein Name: p300
-
基因ID
- 2033
-
UniProt
- Q09472
-
途径
- p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
抗原
-