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p300 抗体 (AA 1-100)

This 小鼠 单克隆 antibody specifically detects p300 in WB, ELISA 和 IF. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN8121098
发货至: 中国
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Quick Overview for p300 抗体 (AA 1-100) (ABIN8121098)

抗原

See all p300 (EP300) 抗体
p300 (EP300) (E1A Binding Protein P300 (EP300))

适用

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人, 小鼠

宿主

  • 124
  • 11
小鼠

克隆类型

  • 122
  • 13
单克隆

标记

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This p300 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)

克隆位点

AB2463
  • 抗原表位

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    AA 1-100

    原理

    p300 mouse mAb

    特异性

    This antibody detects endogenous levels of p300 protein.

    纯化方法

    The antibody was purified by protein G affinity chromatography.

    免疫原

    A synthetic peptide corresponding to the amino acid region 1 - 100 of the human p300 protein.

    亚型

    IgG
  • 应用备注

    WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    p300 (EP300) (E1A Binding Protein P300 (EP300))

    别名

    p300

    背景

    Synonyms: EP300, P300, Histone acetyltransferase p300, p300 HAT, E1A-associated protein p300

    Background: E1A binding protein p300 (EP300) Homo sapiens This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha) , and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008],

    Gene Name: EP300

    Protein Name: p300

    基因ID

    2033

    UniProt

    Q09472

    途径

    p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
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