CDT2/RAMP 抗体
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北京 101111
Quick Overview for CDT2/RAMP 抗体 (ABIN8120957)
抗原
See all CDT2/RAMP (DTL) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DTL Antibody
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特异性
- DTL Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human protein
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亚型
- IgG
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anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (C-Term) antibody
DTL 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) antibodyDTL 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 23GB5230 unconjugated Recombinant Antibody
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (C-Term) antibodyDTL 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (AA 229-256) antibodyDTL 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB24420 unconjugated
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (AA 393-550) antibodyDTL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (AA 1-730) antibodyDTL 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (AA 182-231) antibodyDTL 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (AA 541-730) antibodyDTL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (AA 375-425) antibodyDTL 适用: 人 IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) (AA 229-256), (Middle Region) antibodyDTL 适用: 人, 小鼠 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CDT2/RAMP (DTL) (Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL))
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别名
- DTL
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背景
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Background: developmental stage:Expressed in all fetal tissues examined, included brain, lung, liver, and kidney.,function:Required for CDT1 proteolysis in response to DNA damage through the CUL4-DDB1 E3 ubiquitin-protein ligase. Seems to be necessary to ensure proper cell cycle regulation of DNA replication. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. May play a role in cell proliferation of NT2 embryonal carcinoma cells.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the WD repeat cdt2 family.,similarity:Contains 7 WD repeats.,subcellular location:Nuclear matrix-associated protein. Translocates from the interphase nucleus to the metaphase cytoplasm during mitosis.,subunit:Probable part of a cullin-RING E3 protein ligase complex containing CUL4B-DDB1 and a substrate-recruiting component (DCAF). Interacts with CUL4B and DDB1.,tissue specificity:Expressed in placenta and testis, very low expression seen in skeletal muscle. Detected in all hematopoietic tissues examined, with highest expression in thymus and bone marrow. A low level detected in the spleen and lymph node, and barely detectable level in the peripheral leukocytes. RA treatment down-regulated the expression in NT2 cell.,
Gene Name: DTL CDT2 CDW1 DCAF2 L2DTL RAMP
Protein Name: Denticleless protein homolog (DDB1- and CUL4-associated factor 2) (Lethal(2) denticleless protein homolog) (Retinoic acid-regulated nuclear matrix-associated protein)
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基因ID
- 51514
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UniProt
- Q9NZJ0
抗原
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