Cyclin E1 抗体
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北京 101111
Quick Overview for Cyclin E1 抗体 (ABIN8120794)
抗原
See all Cyclin E1 (CCNE1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Cyclin E1 Rabbit mAb
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特异性
- This antibody detects endogenous levels of Cyclin E1 protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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anti-Cyclin E1 (CCNE1) (AA 10-176) antibody
CCNE1 适用: 人 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal CCNE1-2460 unconjugated
anti-Cyclin E1 (CCNE1) (AA 307-410) antibodyCCNE1 适用: 人, 小鼠 ELISA, FACS 宿主: 小鼠 Monoclonal 5F8C5 unconjugated
anti-Cyclin E1 (CCNE1) (AA 1-100) antibodyCCNE1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1C8D4 unconjugated
anti-Cyclin E1 (CCNE1) (AA 375-411) antibodyCCNE1 适用: 大鼠 WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) (AA 1-410) antibodyCCNE1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) (AA 3-386) antibodyCCNE1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) (AA 373-402), (C-Term) antibodyCCNE1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB07335 unconjugated
anti-Cyclin E1 (CCNE1) (AA 307-410) antibodyCCNE1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5F8B4 unconjugated
anti-Cyclin E1 (CCNE1) antibodyCCNE1 适用: 人 IHC, ELISA, IF 宿主: 兔 Monoclonal 3A5 unconjugated Recombinant Antibody
anti-Cyclin E1 (CCNE1) (Thr395) antibodyCCNE1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB, 1:1000-1:5000 | IHC, 1:400-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- Cyclin E1 (CCNE1)
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别名
- Cyclin E1
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背景
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Synonyms: CCNE1, CCNE, G1/S-specific cyclin-E1
Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus) , which participates in
Gene Name: CCNE1
Protein Name: Cyclin E1
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基因ID
- 898
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UniProt
- P24864
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途径
- Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
抗原
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