CAMK2B 抗体 (pThr286)
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Quick Overview for CAMK2B 抗体 (pThr286) (ABIN8120134)
抗原
See all CAMK2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr286
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原理
- CaMK2 (Phospho Thr286) Antibody
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特异性
- This antibody detects endogenous pospho levels of human CaMK2 (Phospho-Thr286)
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纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized pospho peptide derived from human CaMK2 (Phospho-Thr286)
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亚型
- IgG
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应用备注
- WB 1:500-2000, ELISA(peptide)1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))
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别名
- CaMK2
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背景
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Synonyms: Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta, CaMK-II subunit delta, EC 2.7.11.17)
Background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],
Gene Name: CAMK2D CAMKD
Protein Name: CaMK2 (Phospho-Thr286)
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基因ID
- 817
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UniProt
- Q9UQM7
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途径
- WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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