BRCA2 抗体 (pSer3291)
Our Local Distributor
北京 101111
Quick Overview for BRCA2 抗体 (pSer3291) (ABIN8120033)
抗原
See all BRCA2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer3291
-
原理
- BRCA2 (phospho Ser3291) Antibody
-
特异性
- Phospho-BRCA2 (S3291) Polyclonal Antibody detects endogenous levels of BRCA2 protein only when phosphorylated at S3291.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized phospho-peptide around the phosphorylation site of human BRCA2 (phospho Ser3291)
-
亚型
- IgG
-
-
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 21-130) antibody
BRCA2 适用: 人 WB, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) antibodyBRCA2 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 2990-3232) antibodyBRCA2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 1-300) antibodyBRCA2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 3319-3418) antibodyBRCA2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3D12 unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 251-495) antibodyBRCA2 适用: 人 WB 宿主: 小鼠 Monoclonal 1643CT739-91-87 unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 2308-2537) antibodyBRCA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (pSer3291) antibodyBRCA2 适用: 人, 大鼠, 小鼠 IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 2737-2874) antibodyBRCA2 适用: 斑马鱼 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (C-Term) antibodyBRCA2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
-
别名
- BRCA2
-
背景
-
Synonyms: BRCA2, FACD, FANCD1, Breast cancer type 2 susceptibility protein, Fanconi anemia group D1 protein
Background: Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008],
Gene Name: BRCA2
Protein Name: Breast cancer type 2 susceptibility protein
-
基因ID
- 675
-
UniProt
- P51587
-
途径
- DNA Damage Repair, M Phase, Maintenance of Protein Location
抗原
-
