BMI1 抗体
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北京 101111
Quick Overview for BMI1 抗体 (ABIN8120003)
抗原
See all BMI1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Bmi-1 Antibody(F270)
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特异性
- This antibody detects endogenous levels of human Bmi-1
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Recombinant Protein derived from human Bmi-1
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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别名
- Bmi-1
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背景
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Synonyms: Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Background: BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],
Gene Name: BMI1 PCGF4 RNF51
Protein Name: Bmi-1
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基因ID
- 100532731
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UniProt
- P35226
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途径
- Cell Division Cycle, Autophagy
抗原
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