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BMI1 抗体

This 兔 多克隆 antibody specifically detects BMI1 in WB. It exhibits reactivity toward 人.
产品编号 ABIN8120003
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BMI1 抗体 (ABIN8120003)

抗原

See all BMI1 抗体
BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

适用

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人

宿主

  • 109
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兔

克隆类型

  • 97
  • 75
多克隆

标记

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This BMI1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    Bmi-1 Antibody(F270)

    特异性

    This antibody detects endogenous levels of human Bmi-1

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Recombinant Protein derived from human Bmi-1

    亚型

    IgG
  • 应用备注

    WB 1:500-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

    别名

    Bmi-1

    背景

    Synonyms: Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)

    Background: BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],

    Gene Name: BMI1 PCGF4 RNF51

    Protein Name: Bmi-1

    基因ID

    100532731

    UniProt

    P35226

    途径

    Cell Division Cycle, Autophagy
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