BTRC 抗体 (AA 43-93)
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北京 101111
Quick Overview for BTRC 抗体 (AA 43-93) (ABIN8119993)
抗原
See all BTRC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 43-93
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原理
- FBW1A Antibody
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特异性
- This antibody detects endogenous levels of FBW1A at Human/Mouse
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human FBW1A AA range: 43-93
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亚型
- IgG
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anti-beta-Transducin Repeat Containing (BTRC) (AA 24-151) antibody
BTRC 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4C5D8 unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (AA 50-340) antibodyBTRC 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-beta-Transducin Repeat Containing (BTRC) antibodyBTRC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (AA 17-52), (N-Term) antibodyBTRC 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB16275 unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (AA 397-448) antibodyBTRC 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (AA 52-354) antibodyBTRC 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 2H2 unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (AA 1-605) antibodyBTRC 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (AA 127-156), (N-Term) antibodyBTRC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (AA 52-354) antibodyBTRC 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1F10 unconjugated
anti-beta-Transducin Repeat Containing (BTRC) (C-Term) antibodyBTRC 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BTRC (beta-Transducin Repeat Containing (BTRC))
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别名
- FBW1A
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背景
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Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.The protein encoded by this gene belongs to the Fbws class, in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6. [provided by RefSeq, Mar 2012],
Gene Name: BTRC BTRCP FBW1A FBXW1A
Protein Name: FBW1A
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基因ID
- 8945
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UniProt
- Q9Y297
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途径
- Cell Division Cycle, Hedgehog Signaling
抗原
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