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BIM 抗体 (pSer77)

This 兔 多克隆 antibody specifically detects BIM in WB. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN8119973
发货至: 中国
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Room 801-803
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Quick Overview for BIM 抗体 (pSer77) (ABIN8119973)

抗原

See all BIM (BCL2L11) 抗体
BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

适用

  • 139
  • 84
  • 51
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  • 1
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  • 1
人, 小鼠

宿主

  • 143
  • 7
  • 3
  • 1
兔

克隆类型

  • 117
  • 37
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
This BIM antibody is un-conjugated

应用范围

  • 117
  • 69
  • 61
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  • 21
  • 20
  • 16
  • 14
  • 13
  • 4
  • 3
  • 3
  • 1
  • 1
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  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
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    • 8
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    • 6
    • 5
    • 4
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer77

    原理

    Bim (Phospho Ser77) Antibody

    特异性

    This antibody detects endogenous levels of Human Mouse Bim (phospho-Ser77)

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized phosho peptide around human Bim (Ser77)

    亚型

    IgG
  • 应用备注

    WB 1:1000-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

    别名

    Bim

    背景

    Synonyms: Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death)

    Background: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013],

    Gene Name: BCL2L11 BIM

    Protein Name: Bim (Ser77)

    基因ID

    10018

    UniProt

    O43521

    途径

    PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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