Survivin 抗体
Our Local Distributor
北京 101111
Quick Overview for Survivin 抗体 (ABIN8119953)
抗原
See all Survivin (BIRC5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Survivin Rabbit mAb
-
特异性
- This antibody detects endogenous levels of Survivin protein.
-
纯化方法
- The antibody was purified by protein A affinity chromatography.
-
免疫原
- Recombinant protein (or fragment).
-
亚型
- IgG
-
-
-
-
应用备注
- WB, 1:1000-1:5000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid freeze / thaw cycles
-
储存条件
- -20 °C
-
储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
-
-
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
-
别名
- Survivin
-
背景
-
Synonyms: BIRC5, API4, IAP4, Baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor 4, Apoptosis inhibitor survivin
Background: This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011],
Gene Name: >>Platinum drug resistance, >>Apoptosis, >>Apoptosis-multiple species, >>Hippo signaling pathway, >>Hepatitis B, >>Pathways in cancer, >>Chemical carcinogenesis-receptor activation, >>Colorectal cancer
Protein Name: Survivin
-
基因ID
- 332
-
UniProt
- O15392
-
途径
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
抗原
-