AMACR 抗体 (AA 300-382)
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北京 101111
Quick Overview for AMACR 抗体 (AA 300-382) (ABIN8119692)
抗原
See all AMACR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 300-382
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原理
- AMACR mouse mAb
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特异性
- The antibody can specifically recognize human AMACR protein. In western blotting of Hela and LnCap cell lysates, the antibody can label a 42 kDa band corresponding to AMACR.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 300 - 382 of the human AMACR protein.
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亚型
- IgG
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应用备注
- IHC, 1:100-1:500 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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别名
- AMACR
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背景
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Synonyms: 2 arylpropionyl CoA epimerase, 2 methylacyl CoA racemase, 2-methylacyl-CoA racemase, Alpha methylacyl CoA racemase, Alpha methylacyl Coenzyme A racemase, Alpha methylacyl-CoA racemase deficiency, included, Alpha-methylacyl-CoA racemase, Amacr, AMACR deficiency, included, AMACR_HUMAN, CBAS4, Da1-8, EC 5. 1. 99. 4, Macr1, Methylacyl CoA racemase alpha, RACE, RM
Background: AMACR is an α Formyl COA racemase localized in peroxisomes and mitochondria . It is an enzyme involved in biosynthesis of bile acid and β-oxidation of branched-chain fatty acids. It is expressed in the epithelium and salivary gland of proximal convoluted tubules of pancreas, liver and kidney, and moderately in paraurethral glands. The expression in prostate cancer is higher than that in benign prostate tissue. In the study of prostate cancer, it is often used in combination with PSA, p63, 34 β E12 and other antibodies.
Gene Name: AMACR
Protein Name: AMACR
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基因ID
- 23600
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UniProt
- Q9UHK6
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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