AMACR 抗体 (AA 271-320)
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Quick Overview for AMACR 抗体 (AA 271-320) (ABIN8119691)
抗原
See all AMACR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 271-320
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原理
- P504S Antibody
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特异性
- This antibody detects endogenous levels of Human,Mouse,Rat P504S
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human P504S AA range: 271-320
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亚型
- IgG
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应用备注
- WB 1:1000-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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别名
- P504S
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背景
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Synonyms: Alpha-methylacyl-CoA racemase (EC 5.1.99.4, 2-methylacyl-CoA racemase)
Background: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011],
Gene Name: AMACR
Protein Name: P504S
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基因ID
- 23600
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UniProt
- Q9UHK6
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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