AGRN 抗体 (AA 1900-1980)
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北京 101111
Quick Overview for AGRN 抗体 (AA 1900-1980) (ABIN8119635)
抗原
See all AGRN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1900-1980
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原理
- AGRIN Antibody
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特异性
- AGRIN Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human protein . at AA range: 1900-1980
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亚型
- IgG
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- AGRN (Agrin (AGRN))
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别名
- AGRIN
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背景
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Background: This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015],
Gene Name: AGRN AGRIN
Protein Name: Agrin
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基因ID
- 375790
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UniProt
- O00468
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途径
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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