AGRN 抗体 (AA 1900-1980)
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北京 101111
Quick Overview for AGRN 抗体 (AA 1900-1980) (ABIN7227240)
抗原
See all AGRN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1900-1980
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原理
- Rabbit Anti-AGRIN Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of AGRIN protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human AGRIN protein at AA range: 1900-1980
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亚型
- IgG
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anti-Agrin (AGRN) (AA 1206-1475) antibody
AGRN 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Agrin (AGRN) (AA 1329-1548) antibodyAGRN 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Agrin (AGRN) (AA 968-1130) antibodyAGRN 适用: 人 IHC, WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Agrin (AGRN) (AA 30-350) antibodyAGRN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Agrin (AGRN) (AA 1856-2045) antibodyAGRN 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Agrin (AGRN) (AA 1130-1401) antibodyAGRN 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Agrin (AGRN) (AA 1864-2068) antibodyAGRN 适用: 人, 大鼠, 小鼠 IHC, WB, ELISA, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Agrin (AGRN) (C-Term) antibodyAGRN 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Agrin (AGRN) (N-Term) antibodyAGRN 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- AGRN (Agrin (AGRN))
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别名
- AGRIN
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背景
- Agrin, Agrin N-terminal 110 kDa subunit, Agrin C-terminal 110 kDa subunit, Agrin C-terminal 90 kDa fragment, C90, Agrin C-terminal 22 kDa fragment, C22AGRN encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in AGRN was found. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 224kD
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基因ID
- 375790
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UniProt
- O00468
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途径
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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