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SIGLEC8 抗体 (C-Term)

The 兔 多克隆 anti-SIGLEC8 antibody is suitable to detect SIGLEC8 in samples from 人. It has been validated for WB.
产品编号 ABIN8111681
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SIGLEC8 抗体 (C-Term) (ABIN8111681)

抗原

See all SIGLEC8 抗体
SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

适用

  • 49
  • 9
  • 5
人

宿主

  • 29
  • 11
  • 8
  • 1
兔

克隆类型

  • 31
  • 18
多克隆

标记

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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This SIGLEC8 antibody is un-conjugated

应用范围

  • 28
  • 18
  • 15
  • 6
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  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 4
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    • 2
    • 2
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    • 1
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    C-Term

    原理

    SIGLEC8 Antibody - C-terminal region

    序列

    ESWKDGNPLK KPPPAVAPSS GEEGELHYAT LSFHKVKPQD PQGQEATDSE

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human SIGL8
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74219-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

    别名

    SIGLEC8

    背景

    Background Information: Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]

    Gene Name: sialic acid binding Ig like lectin 8

    Alternative Symbols: SAF2, SIGLEC-8, SIGLEC8L

    Protein Name: sialic acid-binding Ig-like lectin 8

    分子量

    54kDa

    基因ID

    27181

    NCBI登录号

    NP_055257

    UniProt

    Q9NYZ4
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