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SIGLEC8 抗体 (Extracellular Domain) (PE)

SIGLEC8 适用: 人 FACS 宿主: 小鼠 Monoclonal 7C9 PE
产品编号 ABIN7506011
发货至: 中国
  • 抗原 See all SIGLEC8 抗体
    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
    抗原表位
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    适用
    • 42
    • 7
    • 2
    宿主
    • 33
    • 8
    • 1
    小鼠
    克隆类型
    • 35
    • 7
    单克隆
    标记
    • 24
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIGLEC8 antibody is conjugated to PE
    应用范围
    • 33
    • 20
    • 19
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    原理
    Anti-Hu SIGLEC8 PE
    特异性
    The mouse monoclonal antibody 7C9 recognizes an extracellular epitope of SIGLEC8, an eosinophil marker, expressed e.g. in lymph nodes and spleen.
    纯化方法
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    Extracellular domain of human SIGLEC8 fused with Fc fragment of human IgG1
    克隆位点
    7C9
    亚型
    IgG1
    Top Product
    Discover our top product SIGLEC8 Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    限制
    仅限研究用
  • 缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
    别名
    SIGLEC8 (SIGLEC8 产品)
    别名
    SAF2 antibody, SIGLEC-8 antibody, SIGLEC8L antibody, SIGLEC8 antibody, sialic acid binding Ig like lectin 8 antibody, sialic acid-binding Ig-like lectin 8 antibody, SIGLEC8 antibody, LOC506364 antibody
    背景
    Sialic acid binding Ig like lectin 8,SIGLEC8 is a sialic acid binding lectin similar to CD33. In its cytoplasmic comain it contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), and a motive similar to a binding site for SLAM-associated protein. SIGLEC8 is expressed e.g. in lymph nodes and spleen. It is an eosinophil marker, although it can be found also on the surface of mast cells. Crosslinking of SIGLEC8 leads to apoptosis. Soluble form of SIGLEC8 can be foud in human serum, especially in case of eosinophil-associated diseases.,SAF2
    基因ID
    27181
    UniProt
    Q9NYZ4
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