IL13 Receptor alpha 1 抗体 (N-Term)
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北京 101111
Quick Overview for IL13 Receptor alpha 1 抗体 (N-Term) (ABIN8103334)
抗原
See all IL13 Receptor alpha 1 (IL13RA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- IL13RA1 Antibody - N-terminal region
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序列
- YFSHFGDKQD KKIAPETRRS IEVPLNERIC LQVGSQCSTN ESEKPSILVE
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预测反应
- Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human I13R1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63415-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
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别名
- IL13RA1
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背景
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Background Information: The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Gene Name: interleukin 13 receptor subunit alpha 1
Alternative Symbols: NR4, CT19, CD213A1, IL-13Ra
Protein Name: interleukin-13 receptor subunit alpha-1
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分子量
- 46kDa
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基因ID
- 3597
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NCBI登录号
- NP_001551
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UniProt
- P78552
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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