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IL13 Receptor alpha 1 抗体

IL13RA1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854528
发货至: 中国
  • 抗原 See all IL13 Receptor alpha 1 (IL13RA1) 抗体
    IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
    适用
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    宿主
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    克隆类型
    • 58
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    多克隆
    标记
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    This IL13 Receptor alpha 1 antibody is un-conjugated
    应用范围
    • 50
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to IL13 Receptor alpha 1 (interleukin 13 receptor, alpha 1)
    IL13 Receptor alpha 1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human IL13 Receptor alpha 1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product IL13RA1 Primary Antibody
  • 应用备注
    WB: 1:5000-1:20000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: U87-MG , U87-MG membrane extract , IL13RA1-transfected 293T

    Validation: Orthogonal, Overexpression

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2.51 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Ding, Jin, Xie, Park, Tong, Wu, Chhabra, Fu, Li: "A Murine Model for Human ECO Syndrome Reveals a Critical Role of Intestinal Cell Kinase in Skeletal Development." in: Calcified tissue international, Vol. 102, Issue 3, pp. 348-357, (2019) (PubMed).

  • 抗原
    IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
    别名
    interleukin 13 receptor subunit alpha 1 (IL13RA1 产品)
    别名
    CD213A2 antibody, CT19 antibody, IL-13R antibody, IL13BP antibody, CD213A1 antibody, IL-13Ra antibody, NR4 antibody, AI882074 antibody, CD213a1 antibody, IL-13r[a] antibody, Il13ra antibody, IL13RA1 antibody, il-13ra1 antibody, si:ch211-150g2.2 antibody, interleukin 13 receptor subunit alpha 2 antibody, interleukin 13 receptor subunit alpha 1 antibody, interleukin 13 receptor, alpha 1 antibody, interleukin 13 receptor, alpha 1-like antibody, IL13RA2 antibody, IL13RA1 antibody, Il13ra1 antibody, il13ra1 antibody, LOC100360218 antibody
    背景
    The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

    Cellular Localization: Membrane, Single-pass type I membrane protein
    分子量
    49 kDa
    基因ID
    3597
    UniProt
    P78552
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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