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Isocitrate Dehydrogenase 抗体

The 小鼠 单克隆 anti-Isocitrate Dehydrogenase antibody is suitable to detect Isocitrate Dehydrogenase in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IF, IHC (p) 和 FACS.
产品编号 ABIN8093273
发货至: 中国
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Quick Overview for Isocitrate Dehydrogenase 抗体 (ABIN8093273)

抗原

See all Isocitrate Dehydrogenase (IDH) 抗体
Isocitrate Dehydrogenase (IDH)

适用

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人, 大鼠, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This Isocitrate Dehydrogenase antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

6B13
  • 原理

    Isocitrate Dehydrogenase 2 / IDH2

    序列

    KDLAGCIHGL SNVKLNEHFL NTTDFLDTIK SNLDR

    纯化方法

    Affinity purified

    免疫原

    Amino acids KDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDR from the human protein were used as the immunogen for the Isocitrate Dehydrogenase 2 antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal dilution of the Isocitrate Dehydrogenase 2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Isocitrate Dehydrogenase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Isocitrate Dehydrogenase (IDH)

    别名

    Isocitrate Dehydrogenase 2 / IDH2

    背景

    Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.

    UniProt

    P48735
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