Isocitrate Dehydrogenase 抗体
Our Local Distributor
北京 101111
Quick Overview for Isocitrate Dehydrogenase 抗体 (ABIN8093273)
抗原
See all Isocitrate Dehydrogenase (IDH) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Isocitrate Dehydrogenase 2 / IDH2
-
序列
- KDLAGCIHGL SNVKLNEHFL NTTDFLDTIK SNLDR
-
纯化方法
- Affinity purified
-
免疫原
- Amino acids KDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDR from the human protein were used as the immunogen for the Isocitrate Dehydrogenase 2 antibody.
-
亚型
- IgG2a
-
-
-
-
应用备注
- Optimal dilution of the Isocitrate Dehydrogenase 2 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Isocitrate Dehydrogenase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Isocitrate Dehydrogenase (IDH)
-
别名
- Isocitrate Dehydrogenase 2 / IDH2
-
背景
- Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
-
UniProt
- P48735
抗原
-