Isocitrate Dehydrogenase 抗体
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Quick Overview for Isocitrate Dehydrogenase 抗体 (ABIN7881330)
抗原
See all Isocitrate Dehydrogenase (IDH) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Isocitrate Dehydrogenase Antibody / IDH1
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序列
- KGLPNVQRSD YLNTFEFMDK LGENLKIKLA QAK
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纯化方法
- Affinity purified
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免疫原
- Amino acids KGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK from the human protein were used as the immunogen for the Isocitrate Dehydrogenase antibody.
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亚型
- IgG1
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anti-Isocitrate Dehydrogenase (IDH) antibody
IDH 适用: 人, Pig, Vicia faba WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase (IDH) antibodyIDH 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase (IDH) (Middle Region) antibodyIDH 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase (IDH) antibodyIDH 适用: Cabbage, Zea mays, Tomato, Soybean, Red pepper, Potato, Pea, Oryza sativa, Nicotiana benthamiana, Arabidopsis thaliana WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Isocitrate Dehydrogenase antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Isocitrate Dehydrogenase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Isocitrate Dehydrogenase (IDH)
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别名
- Isocitrate Dehydrogenase
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背景
- Isocitrate dehydrogenase 1 (NADP+), soluble is an enzyme that in humans is encoded by the IDH1 gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
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UniProt
- O75874
抗原
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