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ATG3 抗体 (pTyr18) (Biotin)

This anti-ATG3 antibody is a 兔 多克隆 antibody detecting ATG3 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN756384
发货至: 中国

Quick Overview for ATG3 抗体 (pTyr18) (Biotin) (ABIN756384)

抗原

See all ATG3 抗体
ATG3 (ATG3 Autophagy Related 3 (ATG3))

适用

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宿主

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克隆类型

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多克隆

标记

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This ATG3 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pTyr18

    预测反应

    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human ATG3 around the phosphorylation site of Tyr18

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    ATG3 (ATG3 Autophagy Related 3 (ATG3))

    别名

    ATG3

    背景

    Synonyms: 2610016C12Rik, Apg 3, APG3, APG3 autophagy 3 like, APG3 like, APG3-like, APG3L, Apg3p, ATG 3, ATG3, ATG3 autophagy related 3 homolog, ATG3 autophagy related 3 homolog S. cerevisiae, ATG3_HUMAN, Autophagy Apg3p/Aut1p like, Autophagy related protein 3, Autophagy-related protein 3, DKFZp564M1178, FLJ22125, hApg3, MGC15201, OTTHUMP00000214547, OTTHUMP00000214548, PC3 96, Protein PC3-96, Ubiquitin-like-conjugating enzyme ATG3.

    Background: E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.

    基因ID

    64422

    途径

    Autophagy
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