F12 抗体
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北京 101111
Quick Overview for F12 抗体 (ABIN8065428)
抗原
See all F12 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Anti-Factor XII (heavy chain) Antibody
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特异性
- CAM 011-37 binds the heavy chain of human factor XII, including factor XII derivatives such as α-factor XIIa and α-factor XIIa C1-inhibitor complexes. Differs from CAM 011-05.
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预测反应
- Human
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纯化方法
- Protein A or Protein G purified
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免疫原
- Affinity purified human factor XII.
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亚型
- IgG2a, kappa
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anti-Coagulation Factor XII (F12) (AA 400-615) antibody
F12 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XII (F12) (AA 352-587) antibodyF12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XII (F12) (AA 191-300) antibodyF12 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-Coagulation Factor XII (F12) antibodyF12 适用: 人 ELISA, IHC, IP, IHC (p), IEP 宿主: 山羊 Polyclonal unconjugated
anti-Coagulation Factor XII (F12) (C-Term) antibodyF12 适用: 人, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XII (F12) antibodyF12 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XII (F12) (AA 7-34), (N-Term) antibodyF12 适用: 人 WB 宿主: 兔 Polyclonal RB24396 unconjugated
anti-Coagulation Factor XII (F12) (N-Term) antibodyF12 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XII (F12) (AA 486-600) antibodyF12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C without exposure to light
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有效期
- 24 months
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- F12 (Coagulation Factor XII (F12))
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别名
- Factor XII
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背景
- F12, HAE3, HAEX, HAF, coagulation factor XII, Hageman factor, Plasma coagulation Factor XIIa, beta-factor XIIa part 1, beta-factor XIIa part 2, coagulation factor XIIa heavy chain, coagulation factor XIIa light chain,Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (PubMed:2019570, PubMed:21304106, PubMed:8427954). {ECO:0000269|PubMed:2019570, ECO:0000269|PubMed:21304106, ECO:0000269|PubMed:8427954}.,F12,Factor XII is a component in the coagulation cascade. It is a plasma glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII to a-factor XIIa, which in turn activates factor XI to factor XIa.
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分子量
- 50 kDa
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基因ID
- 2161
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UniProt
- P00748
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途径
- Complement System
抗原
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