YBX1 抗体 (Middle Region) (PE)
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北京 101111
Quick Overview for YBX1 抗体 (Middle Region) (PE) (ABIN8054874)
抗原
See all YBX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-YB1/YBX1 Antibody PE Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat,mouse sequences.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human YB1, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Y Box Binding Protein 1 (YBX1) (AA 100-200) antibody
YBX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人 WB, IHC, IF, IP, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (C-Term) antibodyYBX1 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 51-139) antibodyYBX1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C7 unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人 IHC 宿主: 小鼠 Monoclonal YBX1-2430 unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 276-305), (C-Term) antibodyYBX1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB14114 unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 149-178) antibodyYBX1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB41913 unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 224-274) antibodyYBX1 适用: 人, 小鼠 WB, IHC (fp), IP 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (Middle Region) antibodyYBX1 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 绵羊, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (pSer102) antibodyYBX1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- YBX1 (Y Box Binding Protein 1 (YBX1))
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别名
- YBX1
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背景
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Background: YBX1 (Y box binding protein 1), commonly referred to as YB-1 by researchers, is a human protein. YB1 binding has an absolute requirement for the CCAAT box and relative specificity for the Y box. It has a molecular mass of 35,414 and contains 18 % basic residues and putative nuclear localization signals. The YBX1 gene is mapped on 1p34.2. Ybx1 was highly expressed in mouse erythroid myeloid lymphoid clone-1 (EML), a hematopoietic precursor cell line, but that it was downregulated in myeloid progenitors and in Gmcsf-treated EML cells during myeloid differentiation. Ybx1 was expressed at high levels in myeloid leukemic cells at different developmental stages. Knockdown of YBX1 in a human leukemic cell line inhibited proliferation ability, induced apoptosis, and induced megakaryocytic differentiation in response to arsenic trioxide treatment. YBX1 is downregulated during myeloid differentiation and aberrant YBX1 expression in leukemic cells may contribute to leukemia development by blocking differentiation.
Gene Full Name: Y-box binding protein 1
Sequence Similarities: Contains 1 CSD (cold-shock) domain.
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基因ID
- 4904
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UniProt
- P67809
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途径
- Regulation of Muscle Cell Differentiation
抗原
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