WWTR1 抗体 (AA 1-396)
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北京 101111
Quick Overview for WWTR1 抗体 (AA 1-396) (ABIN8054568)
抗原
See all WWTR1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 1-396
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原理
- Anti-WWTR1 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-WWTR1 Antibody. Tested in WB, IHC, ICC/IF, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human WWTR1 recombinant protein (Position: M1-F396).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
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别名
- WWTR1
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背景
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Background: WW domain-containing transcription regulator protein 1 (WWTR1), also known as Transcriptional coactivator with PDZ-binding motif (TAZ), is a protein that in humans is encoded by the WWTR1 gene. WWTR1 acts as a transcriptional coregulator and has no effect on transcription alone. When in complex with transcription factor binding partners, WWTR1 helps promote gene expression in pathways associated with development, cell growth and survival, and inhibiting apoptosis. Aberrant WWTR1 function has been implicated for its role in driving cancers. WWTR1 is often referred to as TAZ due to its initial characterization with the name TAZ. However, WWTR1 (TAZ) is not to be confused with the protein tafazzin, which originally held the official gene symbol TAZ, and is now TAFAZZIN.
Gene Full Name: WW domain containing transcription regulator 1
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分子量
- 50 kDa
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基因ID
- 25937
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UniProt
- Q9GZV5
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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