RECQL2 抗体 (AA 122-240)
Our Local Distributor
北京 101111
Quick Overview for RECQL2 抗体 (AA 122-240) (ABIN8054182)
抗原
See all RECQL2 (WRN) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 122-240
-
原理
- Anti-Werner's syndrome helicase WRN/WRN Antibody
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
预测反应
- coli-derived human WRN recombinant protein (Position: Q122-N240). Human WRN shares 84% amino acid (aa) sequence identity with mouse WRN.
-
产品特性
- Anti-Werner's syndrome helicase WRN/WRN Antibody. Tested in WB applications. This antibody reacts with Human, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived human WRN recombinant protein (Position: Q122-N240). Human WRN shares 84% amino acid (aa) sequence identity with mouse WRN.
-
亚型
- IgG
-
-
anti-Werner syndrome RecQ like helicase (WRN) (AA 1322-1432) antibody
WRN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C11 unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (AA 787-816) antibodyWRN 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17383 unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (Internal Region) antibodyWRN 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (Center) antibodyWRN 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Werner syndrome RecQ like helicase (WRN) antibodyWRN 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal 195C unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (AA 1322-1432) antibodyWRN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F7 unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (C-Term) antibodyWRN 适用: 人 WB, FACS, IP 宿主: 兔 Monoclonal BLR333M unconjugated Recombinant Antibody
anti-Werner syndrome RecQ like helicase (WRN) antibodyWRN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (AA 1322-1432) antibodyWRN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (C-Term) antibodyWRN 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Rat
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
-
别名
- WRN
-
背景
-
Background: Werner syndrome ATP-dependent helicase, also known as DNA helicase, RecQ-like type 3, is an enzyme that in humans is encoded by the WRN gene. This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.
Gene Full Name: WRN RecQ like helicase
-
分子量
- 162 kDa, 200 kDa
-
基因ID
- 7486
-
UniProt
- Q14191
-
途径
- DNA Damage Repair
抗原
-
