p63 抗体 (AA 311-680) (Fluoro550)
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Quick Overview for p63 抗体 (AA 311-680) (Fluoro550) (ABIN8051647)
抗原
See all p63 (TP63) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 311-680
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原理
- Anti-p63/TP63 Antibody Fluoro550 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human p63 shares 98% amino acid (aa) sequence identity with both mouse,rat p63.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human p63 recombinant protein (Position: S311-E680). Human p63 shares 98% amino acid (aa) sequence identity with both mouse and rat p63.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- p63 (TP63) (Tumor Protein P63 (TP63))
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别名
- TP63
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背景
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Background: Tumor protein p63 (TP63), also known as the p63 or TP73L is a protein that in humans is encoded by the TP63 gene. It is mapped to 3q28. TP63 is a member of the p53 family of transcription factors. This gene encodes for two main isoforms by alternative promoters (TAp63 and ΔNp63). TP63 has been mostly restricted to its apoptotic function and more recently as the guardian of oocyte integrity. It has been found that the combined loss of TP63 and p73 results in the failure of cells containing functional p53 to undergo apoptosis in response to DNA damage. TP63 is an essential regulator of stem cell maintenance in stratified epithelial tissues. Tp63 is also critical for maintaining the progenitor-cell populations that are necessary to sustain epithelial development and morphogenesis.
Gene Full Name: tumor protein p63
Sequence Similarities: Belongs to the p53 family.
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基因ID
- 8626
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UniProt
- Q9H3D4
抗原
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