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p63 抗体 (AA 311-680) (Fluoro550)

The Fluoro550-conjugated 兔 多克隆 anti-p63 antibody (ABIN8051647) specifically detects p63 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8051647
发货至: 中国
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Quick Overview for p63 抗体 (AA 311-680) (Fluoro550) (ABIN8051647)

抗原

See all p63 (TP63) 抗体
p63 (TP63) (Tumor Protein P63 (TP63))

适用

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宿主

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克隆类型

  • 61
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多克隆

标记

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This p63 antibody is conjugated to Fluoro550

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 311-680

    原理

    Anti-p63/TP63 Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human p63 shares 98% amino acid (aa) sequence identity with both mouse,rat p63.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human p63 recombinant protein (Position: S311-E680). Human p63 shares 98% amino acid (aa) sequence identity with both mouse and rat p63.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    p63 (TP63) (Tumor Protein P63 (TP63))

    别名

    TP63

    背景

    Background: Tumor protein p63 (TP63), also known as the p63 or TP73L is a protein that in humans is encoded by the TP63 gene. It is mapped to 3q28. TP63 is a member of the p53 family of transcription factors. This gene encodes for two main isoforms by alternative promoters (TAp63 and ΔNp63). TP63 has been mostly restricted to its apoptotic function and more recently as the guardian of oocyte integrity. It has been found that the combined loss of TP63 and p73 results in the failure of cells containing functional p53 to undergo apoptosis in response to DNA damage. TP63 is an essential regulator of stem cell maintenance in stratified epithelial tissues. Tp63 is also critical for maintaining the progenitor-cell populations that are necessary to sustain epithelial development and morphogenesis.

    Gene Full Name: tumor protein p63

    Sequence Similarities: Belongs to the p53 family.

    基因ID

    8626

    UniProt

    Q9H3D4
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