p63 抗体
(8 references)-
- 抗原 See all p63 (TP63) 抗体
- p63 (TP63) (Tumor Protein P63 (TP63))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This p63 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Proximity Ligation Assay (PLA)
- 交叉反应
- 犬, 人, 小鼠, 大鼠
- 产品特性
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Rabbit Polyclonal antibody to p63 (tumor protein p63)
p63 antibody [N2C1], Internal - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human p63. The exact sequence is proprietary.
- 亚型
- IgG
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anti-Tumor Protein P63 (TP63) (AA 421-680) antibody
TP63 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (AA 3-106) antibodyTP63 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal TP63-1786 unconjugated
anti-Tumor Protein P63 (TP63) (AA 5-17) antibodyTP63 适用: 人, 小鼠, 大鼠, Cow WB, IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal TP63-2428 unconjugated
anti-Tumor Protein P63 (TP63) (AA 664-680), (C-Term) antibodyTP63 适用: 人, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 适用: 人, 小鼠 IHC, StM 宿主: 小鼠 Monoclonal TP63-11 unconjugated
anti-Tumor Protein P63 (TP63) (C-Term) antibodyTP63 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (N-Term) antibodyTP63 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (pSer455) antibodyTP63 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: mouse brain , rat brain , A431
Validation: KO/KD, Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.58 mg/mL
- 缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin." in: Aging cell, Vol. 19, Issue 3, pp. e13072, (2020) (PubMed).
: "TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment." in: Cell stem cell, Vol. 24, Issue 2, pp. 271-284.e8, (2020) (PubMed).
: "Cytological Immunostaining of HMGA2, LRP1B, and TP63 as Potential Biomarkers for Triaging Human Papillomavirus-Positive Women." in: Translational oncology, Vol. 12, Issue 7, pp. 959-967, (2019) (PubMed).
: "A revised airway epithelial hierarchy includes CFTR-expressing ionocytes. ..." in: Nature, Vol. 560, Issue 7718, pp. 319-324, (2019) (PubMed).
: "PAX9 regulates squamous cell differentiation and carcinogenesis in the oro-oesophageal epithelium." in: The Journal of pathology, Vol. 244, Issue 2, pp. 164-175, (2019) (PubMed).
: "Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner." in: PLoS pathogens, Vol. 14, Issue 12, pp. e1007457, (2019) (PubMed).
: "Fibroblast Growth Factor Receptor 2 (FGFR2) Is Required for Meibomian Gland Homeostasis in the Adult Mouse." in: Investigative ophthalmology & visual science, Vol. 58, Issue 5, pp. 2638-2646, (2017) (PubMed).
: "A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease." in: Nature microbiology, Vol. 2, pp. 16196, (2016) (PubMed).
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: "Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin." in: Aging cell, Vol. 19, Issue 3, pp. e13072, (2020) (PubMed).
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- 抗原
- p63 (TP63) (Tumor Protein P63 (TP63))
- 别名
- tumor protein p63 (TP63 产品)
- 别名
- AIS antibody, B(p51A) antibody, B(p51B) antibody, EEC3 antibody, KET antibody, LMS antibody, NBP antibody, OFC8 antibody, RHS antibody, SHFM4 antibody, TP53CP antibody, TP53L antibody, TP73L antibody, p40 antibody, p51 antibody, p53CP antibody, p63 antibody, p73H antibody, p73L antibody, TP63 antibody, tp63 antibody, DNp63 antibody, id:ibd3516 antibody, tp73l antibody, wu:fc89f04 antibody, wu:fk85h07 antibody, wu:fk88b02 antibody, Ket antibody, P73l antibody, Tp73l antibody, Trp63 antibody, TRP63 antibody, AI462811 antibody, P51/P63 antibody, P63 antibody, Tp63 antibody, Trp53rp1 antibody, Xp63 antibody, ket antibody, np63 antibody, tp73l-A antibody, trp63 antibody, tumor protein p63 antibody, transformation related protein 63 antibody, tumor protein p63 L homeolog antibody, TP63 antibody, tp63 antibody, Tp63 antibody, Trp63 antibody, tp63.L antibody
- 背景
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This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3), split-hand/foot malformation 4 (SHFM4), ankyloblepharon-ectodermal defects-cleft lip/palate, ADULT syndrome (acro-dermato-ungual-lacrimal-tooth), limb-mammary syndrome, Rap-Hodgkin syndrome (RHS), and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.
Cellular Localization: Nucleus - 分子量
- 77 kDa
- 基因ID
- 8626
- UniProt
- Q9H3D4
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