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TCF7 抗体 (Middle Region)

The 兔 多克隆 anti-TCF7 antibody is suitable to detect TCF7 in samples from 人 和 小鼠. It has been validated for WB.
产品编号 ABIN8047797
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TCF7 抗体 (Middle Region) (ABIN8047797)

抗原

See all TCF7 抗体
TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

适用

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人, 小鼠

宿主

  • 64
  • 12
  • 1

克隆类型

  • 63
  • 14
多克隆

标记

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This TCF7 antibody is un-conjugated

应用范围

  • 47
  • 23
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  • 12
  • 9
  • 7
  • 5
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  • 1
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Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

    • 11
    • 10
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    Middle Region

    原理

    Anti-TCF7 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-TCF7 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human TCF7, which shares 90.6% amino acid (aa) sequence identity with mouse TCF7.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

    别名

    TCF7

    背景

    Background: Transcription factor 7 is a protein that in humans is encoded by the TCF7 gene. It is mapped to 5q31.1. This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling.

    Gene Full Name: transcription factor 7

    分子量

    50 kDa

    基因ID

    6932

    UniProt

    P36402

    途径

    WNT signaling
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