TICAM1 抗体 (C-Term)
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北京 101111
Quick Overview for TICAM1 抗体 (C-Term) (ABIN8047522)
抗原
See all TICAM1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- Anti-TRIF/TICAM1 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-TRIF/TICAM1 Antibody. Tested in IHC, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human TRIF.
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亚型
- IgG
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anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (AA 443-685) antibody
TICAM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (AA 263-526) antibodyTICAM1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) antibodyTICAM1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (Internal Region) antibodyTICAM1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (C-Term) antibodyTICAM1 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (Internal Region) antibodyVerified TICAM1 适用: 人 IHC, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (AA 120-420) antibodyTICAM1 适用: 人, 猴 WB 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (AA 115-143), (N-Term) antibodyTICAM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (C-Term) antibodyTICAM1 适用: 人 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (N-Term) antibodyTICAM1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, -Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, HumanWestern blot, 0.1-0.5 μg/mL, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
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别名
- TICAM1
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背景
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Background: TICAM (TIR DOMAIN-CONTAINING ADAPTOR MOLECULE 1), also known as TICAM1 or TRIF, is an adapter in responding to activation of toll-like receptors (TLRs). It mediates the rather delayed cascade of two TLR-associated signaling cascades, where the other one is dependent upon a MyD88 adapter. By genomic sequence analysis, Oshiumi et al. (2003) mapped the TICAM1 gene to chromosome 19p13.3. By coimmunoprecipitation analysis, Oshiumi et al. (2003) showed that TICAM1 interacts specifically with TLR3, but not with other TLRs. Functional analysis showed that the association of TLR3 and TICAM1 mediates dsRNA activation of IFNB, through either NFKB, AP1, or IRF3. TICAM1 activation of NFKB was found to occur predominantly through IRAK1 rather than IRAK2. Small interfering (si)RNA blockage of TICAM1, just upstream of the TIR domain, reduced IFNB production in response to dsRNA.
Gene Full Name: TIR domain containing adaptor molecule 1
Sequence Similarities: Contains 1 TIR domain.
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分子量
- 110 kDa
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基因ID
- 148022
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UniProt
- Q8IUC6
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
抗原
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