Thrombospondin 1 抗体 (AA 27-112) (HRP)
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北京 101111
Quick Overview for Thrombospondin 1 抗体 (AA 27-112) (HRP) (ABIN8046396)
抗原
See all Thrombospondin 1 (THBS1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-112
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原理
- Anti-Thrombospondin/THBS1 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- coli-derived human Thrombospondin recombinant protein (Position: D27-H112). Human Thrombospondin shares 81.4% amino acid (aa) sequence identity with mouse Thrombospondin.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Thrombospondin recombinant protein (Position: D27-H112). Human Thrombospondin shares 81.4% amino acid (aa) sequence identity with mouse Thrombospondin.
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亚型
- IgG
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anti-Thrombospondin 1 (THBS1) (AA 80-360) antibody
THBS1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thrombospondin 1 (THBS1) (AA 515-671) antibodyTHBS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thrombospondin 1 (THBS1) (N-Term) antibodyVerified THBS1 适用: 人, 小鼠 WB, IHC, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Thrombospondin 1 (THBS1) (AA 71-259) antibodyTHBS1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thrombospondin 1 (THBS1) (AA 24-221) antibodyTHBS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thrombospondin 1 (THBS1) (AA 750-850) antibodyTHBS1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5E2E2 unconjugated
anti-Thrombospondin 1 (THBS1) antibodyTHBS1 适用: 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Thrombospondin 1 (THBS1) (AA 61-259) antibodyTHBS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thrombospondin 1 (THBS1) (AA 1-1170) antibodyTHBS1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Thrombospondin 1 (THBS1) antibodyTHBS1 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Thrombospondin 1 (THBS1)
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别名
- THBS1
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背景
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Background: THBS1 is also known as Thrombospondin 1, TSP1. The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. It is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. It has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. In addition, the thrombospondin-1 protein is a member of the thrombospondinfamily. It is a multi-domain matrix glycoprotein that has been shown to be a natural inhibitor of neovascularization and tumorigenesis in healthy tissue. Both positive and negative modulation of endothelial cell adhesion, motility, and growth have been attributed to TSP1. This should not be surprising considering that TSP1 interacts with at least 12 cell adhesion receptors, including CD36, αv integrins, β1 integrins, syndecan, and integrin-associated protein (IAP or CD47). It also interacts with numerous proteases involved in angiogenesis, including plasminogen, urokinase, matrix metalloproteinase,thrombin, cathepsin, and elastase.
Gene Full Name: thrombospondin 1
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基因ID
- 7057
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UniProt
- P07996
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途径
- Autophagy
抗原
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