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Thrombospondin 1 抗体 (AA 27-112) (Fluoro594)

The Fluoro594-conjugated 兔 多克隆 anti-Thrombospondin 1 antibody (ABIN8046394) specifically detects Thrombospondin 1 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8046394
发货至: 中国
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Quick Overview for Thrombospondin 1 抗体 (AA 27-112) (Fluoro594) (ABIN8046394)

抗原

See all Thrombospondin 1 (THBS1) 抗体
Thrombospondin 1 (THBS1)

适用

  • 103
  • 50
  • 31
  • 7
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 122
  • 12
  • 2

克隆类型

  • 112
  • 24
多克隆

标记

  • 59
  • 21
  • 11
  • 8
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This Thrombospondin 1 antibody is conjugated to Fluoro594

应用范围

  • 78
  • 51
  • 41
  • 36
  • 19
  • 15
  • 11
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 13
    • 11
    • 10
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 27-112

    原理

    Anti-Thrombospondin/THBS1 Antibody Fluoro594 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    coli-derived human Thrombospondin recombinant protein (Position: D27-H112). Human Thrombospondin shares 81.4% amino acid (aa) sequence identity with mouse Thrombospondin.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Thrombospondin recombinant protein (Position: D27-H112). Human Thrombospondin shares 81.4% amino acid (aa) sequence identity with mouse Thrombospondin.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Thrombospondin 1 (THBS1)

    别名

    THBS1

    背景

    Background: THBS1 is also known as Thrombospondin 1, TSP1. The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. It is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. It has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. In addition, the thrombospondin-1 protein is a member of the thrombospondinfamily. It is a multi-domain matrix glycoprotein that has been shown to be a natural inhibitor of neovascularization and tumorigenesis in healthy tissue. Both positive and negative modulation of endothelial cell adhesion, motility, and growth have been attributed to TSP1. This should not be surprising considering that TSP1 interacts with at least 12 cell adhesion receptors, including CD36, αv integrins, β1 integrins, syndecan, and integrin-associated protein (IAP or CD47). It also interacts with numerous proteases involved in angiogenesis, including plasminogen, urokinase, matrix metalloproteinase,thrombin, cathepsin, and elastase.

    Gene Full Name: thrombospondin 1

    基因ID

    7057

    UniProt

    P07996

    途径

    Autophagy
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