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TXNRD1 抗体 (AA 93-326) (Fluoro594)

This 兔 多克隆 antibody specifically detects TXNRD1 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN8046251
发货至: 中国
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Quick Overview for TXNRD1 抗体 (AA 93-326) (Fluoro594) (ABIN8046251)

抗原

See all TXNRD1 抗体
TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

适用

  • 68
  • 39
  • 37

宿主

  • 65
  • 5
  • 1

克隆类型

  • 48
  • 23
多克隆

标记

  • 27
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This TXNRD1 antibody is conjugated to Fluoro594

应用范围

  • 53
  • 22
  • 19
  • 19
  • 15
  • 15
  • 15
  • 13
  • 13
  • 4
  • 3
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  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 12
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 93-326

    原理

    Anti-TXNRD1 Antibody Fluoro594 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TXNRD1 recombinant protein (Position: Y93-Y326).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

    别名

    TXNRD1

    背景

    Background: Thioredoxin reductase 1, cytoplasmic is an enzyme that in humans is encoded by the TXNRD1 gene. The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes an ubiquitously expressed, cytosolic form of TrxR, which functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing, primarily at the 5' end, results in transcript variants encoding same or different isoforms, including a glutaredoxin-containing isoform that is predominantly expressed in testis.

    Gene Full Name: thioredoxin reductase 1

    基因ID

    7296

    UniProt

    Q16881

    途径

    Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
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