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SSRP1 抗体 (AA 2-381) (PE)

The 兔 多克隆 anti-SSRP1 antibody is suitable to detect SSRP1 in samples from 人, 小鼠, 大鼠 和 猴. It has been validated for FACS.
产品编号 ABIN8043234
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SSRP1 抗体 (AA 2-381) (PE) (ABIN8043234)

抗原

See all SSRP1 抗体
SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 65
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克隆类型

  • 64
  • 5
多克隆

标记

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This SSRP1 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 2-381

    原理

    Anti-SSRP1 Antibody PE Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SSRP1 recombinant protein (Position: A2-R381).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

    别名

    SSRP1

    背景

    Background: FACT complex subunit SSRP1 also known as structure specific recognition protein 1 is a protein that in humans is encoded by the SSRP1 gene. The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.

    Gene Full Name: structure specific recognition protein 1

    基因ID

    6749

    UniProt

    Q08945

    途径

    Chromatin Binding
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