MST1R 抗体 (AA 151-250)
Quick Overview for MST1R 抗体 (AA 151-250) (ABIN754303)
抗原
See all MST1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-250
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交叉反应
- 人
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预测反应
- Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MST1R/Ron
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
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别名
- MST1R
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背景
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Synonyms: c met related tyrosine kinase, CD136, CD136 antigen, CDw136, Macrophage stimulating 1 receptor c met related tyrosine kinase, Macrophage stimulating 1 receptor, Macrophage stimulating protein receptor alpha chain, MACROPHAGE STIMULATING PROTEIN RECEPTOR, Macrophage stimulating protein receptor beta chain, Macrophage-Stimulating 1 Receptor MST1R, Macrophage-stimulating protein receptor beta chain, MSP receptor, Mst1r, MST1R variant RON30, MST1R variant RON62, p185 RON, p185-Ron, Protein-tyrosine kinase 8, PTK 8, ptk8, PTK8 protein tyrosine kinase 8, Recepteur d?origine nantais RON, RON, RON protein tyrosine kinase, RON variant E2E3, RON_HUMAN, Soluble RON variant 1, Soluble RON variant 2, Soluble RON variant 3, Soluble RON variant 4, Stem cell derived tyrosine kinase.
Background: MST1R/Ron, a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers. Ron expression has been documented in many normal human tissues. ESTs have been isolated from several tissue libraries, including normal colon, mouth, prostate, and testis and cancerous colon, prostate, stomach, and uterus.
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基因ID
- 4486
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途径
- RTK signaling
抗原
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