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MST1R 抗体 (AA 600-633)

MST1R 适用: 人 WB 宿主: 兔 Polyclonal RB58004 unconjugated
产品编号 ABIN6243848
发货至: 中国
  • 抗原 See all MST1R 抗体
    MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
    抗原表位
    • 41
    • 21
    • 14
    • 12
    • 11
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 600-633
    适用
    • 98
    • 62
    • 41
    • 6
    • 2
    • 1
    • 1
    宿主
    • 109
    • 3
    • 2
    克隆类型
    • 103
    • 11
    多克隆
    标记
    • 38
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This MST1R antibody is un-conjugated
    应用范围
    • 81
    • 36
    • 23
    • 21
    • 17
    • 15
    • 15
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    H
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This MST1R antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 600-633 amino acids from the Central region of human MST1R.
    克隆位点
    RB58004
    亚型
    Ig Fraction
    Top Product
    Discover our top product MST1R Primary Antibody
  • 应用备注
    WB: 1:1000-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
    别名
    MST1R (MST1R 产品)
    别名
    CD136 antibody, CDw136 antibody, PTK8 antibody, RON antibody, Fv-2 antibody, Fv2 antibody, Ron antibody, STK antibody, Cdw136 antibody, Ptk8 antibody, Stk antibody, macrophage stimulating 1 receptor antibody, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) antibody, MST1R antibody, Mst1r antibody
    背景
    Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
    分子量
    152241
    UniProt
    Q04912
    途径
    RTK signaling
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