SSH1 抗体 (AA 489-921)
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北京 101111
Quick Overview for SSH1 抗体 (AA 489-921) (ABIN8037970)
抗原
See all SSH1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 489-921
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原理
- Anti-SSH1 Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human SSH1 shares 66.9% amino acid (aa) sequence identity with mouse SSH1.
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产品特性
- Anti-SSH1 Antibody. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SSH1 recombinant protein (Position: E489-Y921). Human SSH1 shares 66.9% amino acid (aa) sequence identity with mouse SSH1.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- SSH1 (Slingshot Homolog 1 (SSH1))
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别名
- SSH1
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背景
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Background: Protein phosphatase Slingshot homolog 1 is an enzyme that in humans is encoded by the SSH1 gene. The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene Full Name: slingshot protein phosphatase 1
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分子量
- 150 kDa
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基因ID
- 54434
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UniProt
- Q8WYL5
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途径
- CXCR4-mediated Signaling Events
抗原
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