SSH1 抗体 (AA 489-921) (APC)
Our Local Distributor
北京 101111
Quick Overview for SSH1 抗体 (AA 489-921) (APC) (ABIN8037967)
抗原
See all SSH1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 489-921
-
原理
- Anti-SSH1 Antibody APC Conjugated
-
交叉反应 (详细)
- No cross reactivity with other proteins.
-
预测反应
- Human SSH1 shares 66.9% amino acid (aa) sequence identity with mouse SSH1.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SSH1 recombinant protein (Position: E489-Y921). Human SSH1 shares 66.9% amino acid (aa) sequence identity with mouse SSH1.
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- SSH1 (Slingshot Homolog 1 (SSH1))
-
别名
- SSH1
-
背景
-
Background: Protein phosphatase Slingshot homolog 1 is an enzyme that in humans is encoded by the SSH1 gene. The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene Full Name: slingshot protein phosphatase 1
-
基因ID
- 54434
-
UniProt
- Q8WYL5
-
途径
- CXCR4-mediated Signaling Events
抗原
-