SKIL 抗体 (AA 1-504) (FITC)
Our Local Distributor
北京 101111
Quick Overview for SKIL 抗体 (AA 1-504) (FITC) (ABIN8037920)
抗原
See all SKIL 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-504
-
原理
- Anti-SnoN/SNO/SKIL Antibody FITC Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SnoN/SNO/SKIL recombinant protein (Position: M1-V504).
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- SKIL (SKI-Like Oncogene (SKIL))
-
别名
- SKIL
-
背景
-
Background: Ski-like protein is a protein that in humans is encoded by the SKIL gene. The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.
Gene Full Name: SKI like proto-oncogene
-
基因ID
- 6498
-
UniProt
- P12757
-
途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
-