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SKIL 抗体 (AA 1-504)

The 兔 多克隆 anti-SKIL antibody is suitable to detect SKIL in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC, IF, FACS 和 ICC.
产品编号 ABIN7599455
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SKIL 抗体 (AA 1-504) (ABIN7599455)

抗原

See all SKIL 抗体
SKIL (SKI-Like Oncogene (SKIL))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SKIL antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 1-504

    原理

    Anti-SnoN/SNO/SKIL Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SnoN/SNO/SKIL Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SnoN/SNO/SKIL recombinant protein (Position: M1-V504).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    SKIL (SKI-Like Oncogene (SKIL))

    别名

    SKIL

    背景

    Background: Ski-like protein is a protein that in humans is encoded by the SKIL gene. The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.

    Gene Full Name: SKI like proto-oncogene

    分子量

    77 kDa

    基因ID

    6498

    UniProt

    P12757

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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