SKIL 抗体 (AA 1-504)
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北京 101111
Quick Overview for SKIL 抗体 (AA 1-504) (ABIN7599455)
抗原
See all SKIL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-504
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原理
- Anti-SnoN/SNO/SKIL Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-SnoN/SNO/SKIL Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SnoN/SNO/SKIL recombinant protein (Position: M1-V504).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- SKIL (SKI-Like Oncogene (SKIL))
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别名
- SKIL
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背景
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Background: Ski-like protein is a protein that in humans is encoded by the SKIL gene. The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.
Gene Full Name: SKI like proto-oncogene
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分子量
- 77 kDa
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基因ID
- 6498
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UniProt
- P12757
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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