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SKIL 抗体 (AA 1-504) (Cy3)

The Cy3-conjugated 兔 多克隆 anti-SKIL antibody (ABIN8037916) specifically detects SKIL in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8037916
发货至: 中国
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Quick Overview for SKIL 抗体 (AA 1-504) (Cy3) (ABIN8037916)

抗原

See all SKIL 抗体
SKIL (SKI-Like Oncogene (SKIL))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SKIL antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-504

    原理

    Anti-SnoN/SNO/SKIL Antibody Cy3 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SnoN/SNO/SKIL recombinant protein (Position: M1-V504).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    SKIL (SKI-Like Oncogene (SKIL))

    别名

    SKIL

    背景

    Background: Ski-like protein is a protein that in humans is encoded by the SKIL gene. The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.

    Gene Full Name: SKI like proto-oncogene

    基因ID

    6498

    UniProt

    P12757

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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