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Serotonin Receptor 1A 抗体 (C-Term) (APC)

The 兔 多克隆 anti-Serotonin Receptor 1A antibody is suitable to detect Serotonin Receptor 1A in samples from 人 和 大鼠. It has been validated for FACS.
产品编号 ABIN8036211
发货至: 中国
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Quick Overview for Serotonin Receptor 1A 抗体 (C-Term) (APC) (ABIN8036211)

抗原

See all Serotonin Receptor 1A (HTR1A) 抗体
Serotonin Receptor 1A (HTR1A)

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Serotonin Receptor 1A antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-5HT1A Receptor/HTR1A Antibody APC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat,mouse sequences by one amino acid.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT1A Receptor, different from the related rat and mouse sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Serotonin Receptor 1A (HTR1A)

    别名

    HTR1A

    背景

    Background: HTR1A (5-HYDROXYTRYPTAMINE RECEPTOR 1A), also called SEROTONIN 5-HT-1A RECEPTOR or BETA-2-ADRENERGIC RECEPTOR-LIKE PROTEIN G-21, is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin. It is a G protein-coupled receptor (GPCR) that is coupled to Gi/Go and mediates inhibitory neurotransmission. HTR1A denotes the human gene encoding for the receptor.The HTR1A gene is located at 5q12.3. The decreases in 5-HT-1A receptor densities correlated with decreased glucose utilization as measured by PET scan. Activation of 5-HT-1A receptors has been demonstrated to impair cognition, learning, and memory by inhibiting the release of glutamate and acetylcholine in various areas of the brain. 5-HT-1A receptors in the dorsal raphe nucleus are co-localized with neurokinin 1 (NK1) receptors and have been shown to inhibit the release of substance P, their endogenous ligand.

    Gene Full Name: 5-hydroxytryptamine receptor 1A

    Sequence Similarities: Belongs to the WD repeat BUB3 family.

    基因ID

    3350

    UniProt

    P08908

    途径

    JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour
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