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Serotonin Receptor 1A 抗体 (Internal Region)

HTR1A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259651
发货至: 中国
  • 抗原 See all Serotonin Receptor 1A (HTR1A) 抗体
    Serotonin Receptor 1A (HTR1A)
    抗原表位
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 41
    • 25
    • 25
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 35
    • 5
    • 2
    克隆类型
    • 38
    • 4
    多克隆
    标记
    • 22
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Serotonin Receptor 1A antibody is un-conjugated
    应用范围
    • 33
    • 17
    • 13
    • 13
    • 12
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    特异性
    5HT1A Receptor Antibody detects endogenous levels of total 5HT1A Receptor.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human 5HT1A Receptor, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product HTR1A Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC-p 1:50-1:200, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • Sun, Xu, Yi, Chen, Wu, Cao, Zhou, Jiang, Zhang: "Role of 5-HT1A receptor in insular cortex mediating stress - induced visceral sensory dysfunction." in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, Vol. 28, Issue 7, pp. 1104-13, (2018) (PubMed).

  • 抗原
    Serotonin Receptor 1A (HTR1A)
    别名
    HTR1A (HTR1A 产品)
    别名
    5-HT-dro2A antibody, 5-HT1ADro antibody, 5-HT[1A]Dro antibody, 5-HT[[1ADro]] antibody, 5-HT[[1A]] antibody, 5-HT[[1A]]DRO antibody, 5HT-R2A antibody, 5HT-dro2A antibody, 5HT-drp[[2A]] antibody, 5HT1A antibody, 5HT[[1ADro]] antibody, 5htdro2a antibody, CG16720 antibody, DRO2A antibody, Dm5HTdro2A antibody, Dmel\\CG16720 antibody, d5-HT1A antibody, 5htr1a antibody, htr1a antibody, HTR1A antibody, Htr1a antibody, 5-Ht1a antibody, Gpcr18 antibody, 5-HT-1A antibody, 5-HT1A antibody, 5HT1a antibody, ADRB2RL1 antibody, ADRBRL1 antibody, G-21 antibody, PFMCD antibody, RAT5HT1A antibody, 5ht1a antibody, adrb2rl1 antibody, adrbrl1 antibody, htr1a-A antibody, 5-hydroxytryptamine (serotonin) receptor 1A antibody, 5-hydroxytryptamine receptor 1A antibody, 5-hydroxytryptamine (serotonin) receptor 1A a antibody, 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled L homeolog antibody, 5-HT1A antibody, HTR1A antibody, htr1aa antibody, Htr1a antibody, htr1a.L antibody
    背景

    Description: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.

    Gene: HTR1A

    分子量
    46 kDa
    基因ID
    3350
    UniProt
    P08908
    途径
    JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour
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