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Serotonin Receptor 1A 抗体 (C-Term) (HRP)

This 兔 多克隆 antibody specifically detects Serotonin Receptor 1A in WB, ELISA 和 IHC. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN8036210
发货至: 中国
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Quick Overview for Serotonin Receptor 1A 抗体 (C-Term) (HRP) (ABIN8036210)

抗原

See all Serotonin Receptor 1A (HTR1A) 抗体
Serotonin Receptor 1A (HTR1A)

适用

  • 59
  • 43
  • 32
  • 1
  • 1
人, 大鼠

宿主

  • 54
  • 5
  • 2

克隆类型

  • 57
  • 4
多克隆

标记

  • 26
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Serotonin Receptor 1A antibody is conjugated to HRP

应用范围

  • 38
  • 19
  • 17
  • 13
  • 13
  • 10
  • 9
  • 4
  • 4
  • 3
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 13
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-5HT1A Receptor/HTR1A Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat,mouse sequences by one amino acid.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT1A Receptor, different from the related rat and mouse sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Serotonin Receptor 1A (HTR1A)

    别名

    HTR1A

    背景

    Background: HTR1A (5-HYDROXYTRYPTAMINE RECEPTOR 1A), also called SEROTONIN 5-HT-1A RECEPTOR or BETA-2-ADRENERGIC RECEPTOR-LIKE PROTEIN G-21, is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin. It is a G protein-coupled receptor (GPCR) that is coupled to Gi/Go and mediates inhibitory neurotransmission. HTR1A denotes the human gene encoding for the receptor.The HTR1A gene is located at 5q12.3. The decreases in 5-HT-1A receptor densities correlated with decreased glucose utilization as measured by PET scan. Activation of 5-HT-1A receptors has been demonstrated to impair cognition, learning, and memory by inhibiting the release of glutamate and acetylcholine in various areas of the brain. 5-HT-1A receptors in the dorsal raphe nucleus are co-localized with neurokinin 1 (NK1) receptors and have been shown to inhibit the release of substance P, their endogenous ligand.

    Gene Full Name: 5-hydroxytryptamine receptor 1A

    Sequence Similarities: Belongs to the WD repeat BUB3 family.

    基因ID

    3350

    UniProt

    P08908

    途径

    JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour
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