L-Selectin 抗体 (AA 39-372) (Biotin)
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北京 101111
Quick Overview for L-Selectin 抗体 (AA 39-372) (Biotin) (ABIN8035318)
抗原
See all L-Selectin (SELL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 39-372
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原理
- Anti-CD62L/SELL Antibody Biotin Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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预测反应
- coli-derived human L-selectin recombinant protein (Position: W39-Y372). Human L-selectin shares 77.5 %,78.7 % amino acid (aa) sequence identity with mouse,rat L-selectin,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human L-selectin recombinant protein (Position: W39-Y372). Human L-selectin shares 77.5 % and 78.7 % amino acid (aa) sequence identity with mouse and rat L-selectin, respectively.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- L-Selectin (SELL) (Selectin L (SELL))
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别名
- SELL
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背景
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Background: CD62L, also known as L-selectin, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a homing receptor for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.
Gene Full Name: selectin L
Sequence Similarities: Belongs to the selectin/LECAM family.
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基因ID
- 6402
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UniProt
- P14151
抗原
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