RYK 抗体 (AA 66-607) (APC)
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Quick Overview for RYK 抗体 (AA 66-607) (APC) (ABIN8034202)
抗原
See all RYK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 66-607
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原理
- Anti-RYK Antibody APC Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human RYK shares 97.2% amino acid (aa) sequence identity with mouse RYK.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RYK recombinant protein (Position: L66-V607). Human RYK shares 97.2% amino acid (aa) sequence identity with mouse RYK.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
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别名
- RYK
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背景
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Background: The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene Full Name: receptor like tyrosine kinase
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基因ID
- 6259
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UniProt
- P34925
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途径
- RTK signaling, WNT signaling, Regulation of Cell Size
抗原
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