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RNF34 抗体 (AA 46-372) (PE)

The 兔 多克隆 anti-RNF34 antibody is suitable to detect RNF34 in samples from 人. It has been validated for FACS.
产品编号 ABIN8033325
发货至: 中国
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Quick Overview for RNF34 抗体 (AA 46-372) (PE) (ABIN8033325)

抗原

See all RNF34 抗体
RNF34 (Ring Finger Protein 34 (RNF34))

适用

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宿主

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克隆类型

  • 36
多克隆

标记

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This RNF34 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 46-372

    原理

    Anti-RNF34 Antibody PE Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human RNF34 recombinant protein (Position: E46-S372).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    RNF34 (Ring Finger Protein 34 (RNF34))

    别名

    RNF34

    背景

    Background: E3 ubiquitin-protein ligase RNF34 is an enzyme that in humans is encoded by the RNF34 gene. The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.

    Gene Full Name: ring finger protein 34

    基因ID

    80196

    UniProt

    Q969K3
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